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Salvage Therapy from Traumatic Ischemic Finger Necrosis via Prostaglandin E1 Assisted Conservative Treatment: A Case Report
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Jae Hyuk Shin, Ho Guen Chang, Cheol Jung Yang, Jungtae Ahn
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J Korean Fract Soc 2015;28(4):245-249. Published online October 31, 2015
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DOI: https://doi.org/10.12671/jkfs.2015.28.4.245
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Abstract
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- Prostaglandin E1 (PGE-1) is a potent vasodilator, which also inhibits platelet aggregation, affects the blood flow viscosity, and fibrinolysis. The compound also excerts anti-inflammatory effects by inhibiting the monocyte and neutrophil function. PGE-1 has been widely administered following microvascular flap surgery, along with perioperative antithrombotic agents such as low molecular weight heparin or aspirin, showing excellent results. We report a case showing successful salvage recovery from post-traumatic ischemic necrosis of the finger via PGE-1 assisted conservative treatment.
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