Background Bone mineral density (BMD) is well-documented in relation to fractures of the spine, hip, distal radius, and proximal humerus; however, its correlations with other fracture types are less established. This study aimed to analyze BMD and associated risk factors in older adults (≥65 years of age) with osteoporotic ankle fractures. These fractures involve low-energy trauma, resulting from falls from a standing height or lower, and occur from impacts which typically do not cause fractures in individuals with normal bone.
Methods This retrospective study analyzed data from 1,411 patients diagnosed with ankle fractures admitted to Chosun University Hospital between February 2012 and April 2023. After applying inclusion criteria (age ≥65 years; low-energy ankle fracture) and exclusion criteria (high-energy trauma, open/multiple fractures, missing dual-energy X-ray absorptiometry [DXA]), 73 of 1,411 patients were analyzed. Lumbar spine, femoral neck, and total hip T-scores were obtained with a Horizon Wi DXA scanner, and associations with age, sex, mechanism of injury, comorbidities, smoking status, alcohol consumption, body mass index (BMI), and history of fractures were tested by independent t-tests and one-way ANOVA with Scheffé post hoc tests.
Results Significant differences in BMD were observed according to age, sex, and BMI. Age was significantly associated with the lowest, femoral neck, and total hip T-scores, sex with the lowest T-score, lumbar spine, and total hip T-scores, and BMI with the lowest and total hip T-scores (P<0.05). No significant associations were found with diabetes, hypertension, smoking, alcohol consumption, injury mechanism, or prior fractures; dementia was not tested because only one patient had dementia.
Conclusions These results suggest that age, sex, and BMI are associated with BMD in older patients with ankle fractures, although the associations varied according to the measured site. These findings support the importance of osteoporosis screening and management in this population, particularly in women.
Level of evidence: IV.
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