Journal of Musculoskeletal Trauma

The Effect of Platelet-Rich Plasma (PRP) on the Healing of Allograft for the Treatment of Segmental Bone Defect of the Ulna in Rabbits: Joo Hyun Song, Jinyoung Jeong, Yong Koo Kang, Han Yong Lee, Mun Ik Son, Sang Il Seo; J Korean Soc Fract 2003;16(3):416-422. Published online July 31, 2003; DOI: https://doi.org/10.12671/jksf.2003.16.3.416

PURPOSE
The purpose of this study was to evaluate the effect of Platelet-Rich Plasma (PRP) on the healing of the allograft for the treatment of the segmental bone defect of the ulna in Rabbits.
MATERIALS AND METHODS
About 2 cm-sized segmental bone defects were created on both ulna of twenty rabbits. The rabbits were divided into two groups, even and odd number group after numbering them from 1 to 20. The segmental bone from the odd numbered animal was transplanted to the even numbered animal, and the even numbered to the odd numbered. The left side of the ulna of the animal is grafted with a segmental allograft only. The right side of the ulna was grafted with a segmental allograft and 0.7 cc of PRP. Radiographs obtained at 0, 4, 8, and 12 weeks postoperatively were graded for radiologic union.
RESULTS
The use of the combination of PRP and segmental allograft demonstrated improved healing on radiolographic study compared with that demonstrated after use of allogrft alone.
CONCLUSION
The results of the study suggests that the use of the combination of PRP and segmental allograft can be considered as an alternative method to manage the segmental defect of the long bone.

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Effect of Different Bone Substitutes on the Concentration of Growth Factors in Platelet-rich Plasma
Hee Soon Cho, So-Young Park, Sukyoung Kim, Sang Keun Bae, Duk Seop Shin, Myun-Whan Ahn
Journal of Biomaterials Applications.2008; 22(6): 545. CrossRef

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Management of Both Tibia Fracture: Kyung Jin Song, Sang Hun Song, Jong Hyuk Park; J Korean Soc Fract 2003;16(2):186-193. Published online April 30, 2003; DOI: https://doi.org/10.12671/jksf.2003.16.2.186

Abstract PDF: PURPOSE
The purpose of this study was to analyze the associated injury, difficulties in management and complications with surgery, and to suggest the guideline according to the severity and type of injury in the management of both tibia fractures. MATERIAL AND METHOD: We analyzed 12 patients, 8 men and 4 women and their age was 43.4 years old in average. The cause of injury was traffic accident in 10, autobike in 1 and farm machine injury in 1 case. There were both open tibia fracture in 6, one side open fracture in 2 and both closed fracture in 4 cases. We analyzed the average interval from injury to operation, duration of hospitalization, duration of both side bone union and complications.
RESULTS
In both open tibia fracture, the average interval from injury to operation was 12.5 days, average duration of hospitalization was 3.2 months, and average duration of bone union was 14.5 months. In one side open fracture, the average interval to operation was 25 days, average duration of hospitalization was 3.75 months, and average duration of bone union was 8.7 months. In both closed fracture, the average interval to operation was 15 days, average duration of hospitalization was 1.92 months, and average duration of bone union was 4.8 months.
CONCLUSION
Both tibia fractures were caused by high energy and also associated with multiple injury, and fracture stability and soft tissue damage should be evaluated thoroughly before surgery. Anatomical reduction and rigid fixation should be necessary to reduce the post-surgical complications.

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Bone Union Rates in Open Phalangeal Fracture of Hand: S W Suh, S H Lee, J G Oh, D Park, K S Kim, C J Kim; J Korean Soc Fract 1996;9(3):782-787. Published online July 31, 1996; DOI: https://doi.org/10.12671/jksf.1996.9.3.782

Abstract PDF: This review was undertaken to analyze the rate of bone union according to accuracy of reduction, methods of fixation, timimg of wound closure and to determine if immediate wound closure increases the infection rate. The materials used in this study included 49 cases of open digital fractures of hand which had been treated at Ansan Hospital, Korea University, College of Medicine from January, 1988 to May, 1995. Of the 38 patients, male were 34(89.5%) and female were 4(10.5%). The average age at operation was 31.9(ranging from 18 to 56 years). On terms of sites of injury within digits, proximal phalanx injured in 18 cases, mid-phalanx16 cases, distal phalanx 20 cases. As a fixatives, K-wire was used in 36 cases(73.5%), mini-plate 8 cases(16.3%), splint immobilization in 5 cases(10.2%). Average time to bone union for K-wire fixation was 12.8 weeks, miniplate was 13.6 weeks, splint immobilization 13.2 weeks. On terms of accuracy of reduction, width of gap between fragments were measured, cases with width of gap less than 2mm were 28 cases(57.6%), cases more than 2mm were 21 cases(42.4%). Bone union periods according to the accuracy of reduction are as follows: cases with width of gap less than 2mm was 11.4 weeks, more than 2mm-15.7 weeks, apposition more than 2/3-12.6 weeks, less than 2/3-16 weeks. Degree of soft tissue injuries was classified based on modified Gustillo-Andersons classification. One case belonged to type I injury, 15 cases to type II and 33 cases to type III. Bone union periods for type I, II was 12.9 weeks in average, and 13.8 weeks for type III.

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