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- Autogenous bone marrow injection for the treatment of delayed union of the long bone
- Jin Hyung Sung, Jae Duk Ryu, Weon Yoo Kim, Chang Hwan Han, Eui Young Ohm, Jin Young Kim
- J Korean Soc Fract 1999;12(4):1071-1076. Published online October 31, 1999
- DOI: https://doi.org/10.12671/jksf.1999.12.4.1071
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Abstract
PDF - It is known that the Salter-Harris type I and II fractures of the distal tibial epiphysis usually For resolving problems of delayed union and non-union of long bones, many efforts was made such as autogenous graft, allogenic or artificial bone graft and electrical stimulation, but there were many complications and not sufncient fracture healing process. The purpose of this study was to investigate the effect of autograft with bone marrow on the repair or bone formation of delayed union by the serial radiogram and clinical examination. We evaluated thirty nine patients which had been treated for long bone fracture, to whom bone marrow injection was made between 3 months and 13 months after adequate fixation(average.4.8months). After bone marrow injection, clinical follow up period was from 15 months to 35 months(average 26.7months). The age distribution was from 18 years to 84 years(average 42). A total of 100- 150cc of marrow was injected at the nonunion site immediately after aspiration under the C-arm. Of 39 cases, there were improved bone healing process of 30 cases(77%) by radiographically and clinically, Of 9 cases without improvement, 5 cases were due to loosening of external fixator, 2 cases was due to chronic osteomyelitis and other 2 cases was unknown origin. No serious complications were observed other than no improvement. Although percutaneous bone marrow injection does not promote healing more rapidly than would standard operative bone grafting, it has many distinct advantages over the latter. It is safe, easy, and time saving. It is economical and involves minimal trauma. It can be done under local anesthesia and avoids the risks of general anesthesia, infection and surgery. It can be done in cases which are not fit for open bone grafting because of poor condition of the skin.
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- Effective Preparation of A Bone Marrow Graft
- Jae Sung Seo, Woo Seok Jang
- J Korean Soc Fract 1996;9(3):788-793. Published online July 31, 1996
- DOI: https://doi.org/10.12671/jksf.1996.9.3.788
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Abstract
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- The purpose of this study was to determine the effective preparation of a bone marrow graft by centrifugation. The experimental 4 groups were divided into Group A(5min/400G), group B(7min/400G), group C(10min/400G), and Group D(5min/600G) after aspiration of 12 case bone marrows. The results were as follows: Group A and Group B were not effective preparations of a bone marrow graft as seen in the total cell count and the viable cell count. Group C was the most effective preparation of a bone marrow graft among 4 groups. Group D had a the less viable cell count than Group C but the viable cell count was enough to record.
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