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Alterations of Biochemical Markers in Osteoporotic Fractures
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Jae Sung Seo, Kwang Hee Lee, Woo Hyuk Jang
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J Korean Soc Fract 1999;12(3):652-659. Published online July 31, 1999
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DOI: https://doi.org/10.12671/jksf.1999.12.3.652
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 Abstract
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- Hip fracture is one of the most severe consequence of osteoporosis affecting aged women. Biochemical markers of bone formation and bone resorption allow for a noninvasive assessment of the bone turnover alteration of the entire skeleton in osteoporosis.
To evaluate the bone metabolic status of postmenopausal women who sustained hip fractures, we measured serum osteocalcin levels as a bone formation markers, and urinary deoxypyridinoline levels as a bone resorption markers. Comparison was made with-age-matched controls. At the time of admission, serum osteocalcin was 23% lower in the fractured patients compared to controls and urine deoxypyridinoline was 22% higher than in the controls(P<0.05). Hip fracture patients have biochemical evidence of decreased bone formation and increased bone resorrtion compared to controls. Increased bone resorrtion was considered more important factor than bone formation in the postmenopausal osteoporotic hip fracture. Since fracture pathogenesis is complex, various factors, such as osteoporosis and risk factors for injury, have been considered.
We suggest that abnormal level of osteocalcin and deoxypyridinoline in Postmenopausal women could be contribute a factor of fracture pathogenesis.
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Experience with Bipolar Hemiarthroplasty in Femoral Neck Fracture in the Elderly Patients: Correlation Between Preoperative Medical Conditions and Postoperative Functional Results of Hip
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Kwang Hee Lee, Se Dong Kim, Dong Chul Lee, Duk Seop Shin
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J Korean Soc Fract 1998;11(1):143-152. Published online January 31, 1998
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DOI: https://doi.org/10.12671/jksf.1998.11.1.143
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Abstract
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- The displaced femoral neck fracture remains a major challenge to orthopedic surgeons, as the elderly population is increasing. Elderly patients with femoral neck fractures often have other medical conditions, fragile bones, and poor compliance. Thus, for elderly patients who need early ambulation and funtional recovery, bipolar prosthesis is accepted as an appropriate treatment. We report a study of 58 cases of bipolar hemiarthroplasty with a femoral neck fracture and a physiologic age older than 65 years from January 1991 to May 1996. The purpose of this study is to evaluate the functional outcome of bipolar hemiarthroplasty and correlation between preoperative medical conditions and Harris hip score in femoral neck fractures in the elderly patients. The results obtained were as followings.
1. 90% of patients had uncontrolled medical conditions. Cardiovascular and pulmonary disease were main preexisting medical conditions.
2. The preoperative medical conditions were important deteminants for the functional results after bipolar hemiarthroplasty.
3. Dislocated bipolar prosthesis needed open reduction or revision to total hip arthroplast due to disassembly of the prosthesis caused by attempted closed reduction.
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Citations
Citations to this article as recorded by  - Usefulness of the Cementless Stem for the Treatment of Hip Fracture in Elderly Patients with Osteoporosis - Comparative Analysis between Cementless Stem and Cemented Stem -
Joon Soon Kang, Kyoung Ho Moon, Rhu Seop Kim, Sang Ho Lee, Jong Min Choi
Journal of the Korean Fracture Society.2011; 24(1): 16. CrossRef
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